Can Hormone Therapy Prevent Heart Disease? Breaking Down the New JAMA Research

What they found: maybe 22% CVD reduction with early hormone therapy. What they couldn't answer: which formulation (if any) drives it, why Black women benefited differently, or if selection bias accounts for the whole signal. What we need: stratified RCTs by formulation type and race, powered to detect differences, not just detect average effects. Stop treating OCPs and menopausal HT as interchangeable hormone exposures. The commentary authors acknowledged the analysis was underpowered for formulation subgroups. That's not a limitation to note and move pa… Video by YouTube channel.